Thinking as a Hobby 3477538 Curiosities served |
2004-01-07 1:55 PM Bioengineering Better Mosquitos Previous Entry :: Next Entry Read/Post Comments (4) Here's an interesting piece in Salon on the efforts to produce transgenic mosquitos to help reduce or eliminate malaria.
But the problem with the first line of research is that the mosquitos have to be as fit, or fitter, than their wild counterparts for the genes that block malaria transmission to spread throughout wild populations and do their job. This may not be a problem for the second line of research, which gives the mosquito "a turbo-charged immune system". These critters may definitely be fitter than their wild counterparts. But see, this is what worries me about this sort of research. I'm less worried about the unforeseen consequences, and more worried about the foreseen ones. Namely, they're trying to stop malaria by making mosquitos stronger. Doesn't this seem like an odd way of going about things? During the Black Plague, would it have made sense to make fitter rats and fitter fleas? You may be blocking the worse of two evils, but you're still boosting one of the evils. The thing is, mosquitos aren't just vectors for malaria.
Okay, so you've just made mosquitos who are better at reproducing, surviving, and spreading, but you've blocked their ability to transmit malaria. If there are now more, fitter mosquitos, though, haven't you just increased the transmission of all the other mosquito-based diseases, such as filaria, dengue, brain fever, yellow fever, and our newest friend, West Nile Virus? Scientists just succeeded in sequencing the entire mosquito genome last year. We've got the keys to the kingdom. And we're going to use that knowledge to make mosquitos fitter? What, may I ask, in the hell are these researchers thinking? I don't propose to know all the technical issues involved, but it would seem to me that the focus should be on reducing the numbers of human-feeding mosquitos, wiping them damn near to extinction if possible (don't worry, there are about 2,500 species of mosquito altogether...we can do without the ones that feed on us). But how would we use genetic information to do this? One possibility might be some sort of Trojan Horse gene that spreads rapidly in a population, is extremely deadly, but only expresses itself after several generations. Or perhaps we could exploit those microorganisms or other parasites that are harmful to mosquitos but benign to humans. If we're going to try boosting anybody's fitness, it should be those critters that kill mosquitos, not the mosquitos themselves. Maybe these lines of thinking are not fruitful, and surely they'd carry their own risks and challenges. But the current lines of research, focused on making fitter mosquitos, frankly make me scratch my damned head. Read/Post Comments (4) Previous Entry :: Next Entry Back to Top |
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